3.19%	% of shares held by all insiders
33.90%	% of shares held by institutions
35.02%	% of float held by institutions
194	Number of institutions holding shares

Holder	Shares	Date reported	% out	Value
Blackrock Inc.	5,938,968	29 June 2023	7.25%	40,622,542
State Street Corporation	4,408,937	29 June 2023	5.38%	30,157,129
Vanguard Group Inc	4,204,151	29 June 2023	5.13%	28,756,393
Geode Capital Management, LLC	1,542,300	29 June 2023	1.88%	10,549,332
Northern Trust Corporation	735,988	29 June 2023	0.90%	5,034,158
NWAM LLC	634,600	29 June 2023	0.77%	4,340,664
Susquehanna International Group, LLP	633,639	29 June 2023	0.77%	4,334,090
Charles Schwab Investment Management, Inc.	581,262	29 June 2023	0.71%	3,975,832
Jane Street Group, LLC	434,292	29 June 2023	0.53%	2,970,557
Rafferty Asset Management, LLC	350,662	29 June 2023	0.43%	2,398,528

Holder	Shares	Date reported	% out	Value
SPDR (R) Ser Tr-SPDR (R) S&P (R) Biotech ETF	2,954,499	30 Aug 2023	3.61%	20,208,773
Vanguard Total Stock Market Index Fund	2,266,872	29 June 2023	2.77%	15,505,404
iShares Russell 2000 ETF	1,610,255	30 Aug 2023	1.96%	11,014,144
Vanguard Extended Market Index Fund	1,099,596	29 June 2023	1.34%	7,521,236
Fidelity Small Cap Index Fund	617,090	29 June 2023	0.75%	4,220,895
iShares Russell 2000 Growth ETF	590,239	30 Aug 2023	0.72%	4,037,234
iShares NASDAQ Biotechnology ETF	559,018	30 Aug 2023	0.68%	3,823,683
Fidelity Extended Market Index Fund	410,257	30 May 2023	0.50%	2,806,157
Direxion Shares ETF Tr-Direxion Daily S&P Biotech Bull 3x Sh	368,732	30 Aug 2023	0.45%	2,522,126
Schwab Strategic Tr-Schwab U.S. Small Cap ETF	330,111	30 May 2023	0.40%	2,257,959

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Anavex Life Sciences Corp. (AVXL)