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  • STMicroelectronics Works with Alifax on Rapid, Cost-Efficient  Point-of-Care Medical Testing
    GlobeNewswire

    STMicroelectronics Works with Alifax on Rapid, Cost-Efficient Point-of-Care Medical Testing

    T4295D -- Oct 29 2020 -- ST Alifax LoC coop for PCR tests_IMAGE STMicroelectronics Works with Alifax on Rapid, Cost-Efficient Point-of-Care Medical Testing * Alifax, a diagnostic-test producer, has customized biological content and reagents to detect pandemic-related genetic material and other viral (and bacterial) pathogens * ST Real-Time PCR molecular-diagnostics technology, using disposable chip-based cartridges, can be adapted to detect any genetic materialGeneva, Switzerland, and Padova, Italy, October 29, 2020 – STMicroelectronics (NYSE: STM), a global semiconductor leader serving customers across the spectrum of electronics applications, and Alifax S.r.l, a producer of clinical diagnostic instrumentation, have worked together on a rapid, cost-efficient portable solution that will be available from Alifax, for point-of-care molecular diagnostic detection using highly reliable real-time Polymerase Chain Reactions (PCR) to amplify genetic material (RNA and DNA1) in patient samples. Leveraging technology developed and licensed from ST, Alifax is manufacturing the Molecular Mouse, a small portable instrument that contains a broad range of ST components, including STM32 MCUs, sensors, amplifiers, and other devices. Connected to a PC, the Molecular Mouse uses medical reagents2 created by Alifax to manage the control and testing of multiple targets or samples on a tiny disposable cartridge, manufactured by ST using its high-volume Micro-Electro-Mechanical Systems (MEMS) semiconductor process technology. Test results are available in less than hour. “One crucial lesson from the current global pandemic is the importance of rapid, cost-efficient point-of-care testing that allows immediate remote diagnosis, and then, if necessary, patient isolation,” said Alessandro Cremonesi, Chief Innovation Officer, STMicroelectronics. “ST has been investing in its Real-Time PCR platform convinced that innovative semiconductor-based diagnostic solutions can positively impact our lives.““Leveraging our high-volume semiconductor-manufacturing technology and long-term leadership in microfluidics, we’ve developed a rapidly customizable, highly flexible cartridge and instrumentation platform that delivers rapid and precise point-of-care diagnostic results, which Alifax has used to respond almost immediately to present pandemic and future diagnostic needs,” added Benedetto Vigna, President Analog MEMS, and Sensors Group, STMicroelectronics.ST has demonstrated its efficacy and efficiency to scale reliable, high-volume manufacturing of semiconductors and its expertise in microfluidics for more than 25 years. Moreover, roughly 10 years of proven success in developing MEMS-based Real-Time PCR technologies has now culminated in a product generation that Alifax has rapidly adapted to address the current global pandemic. “Building on our passion for research and excellence in innovation, Alifax has established its strength in hematology and bacteriology for diagnostic purposes. By working closely with ST and combining its foundational microfluidic and other technology in the Molecular Mouse and our pathogen-specific assays, starting from a COVID-19 test, we’re ready to contribute to rapidly diagnosing, isolating, and ultimately stopping the spread of pathogens,” said Paolo Galiano, President Alifax. Certified to CE-IVD3 the Molecular Mouse, disposable test cartridges, and assays are available now from Alifax. You can watch a video on Molecular Mouse at https://www.alifax.com/products/nuova-category-page/show/molecular-mouse.Further Technical Information With a footprint4 smaller than a smartphone, the Alifax Molecular Mouse can run real-time quantitative Polymerase Chain Reactions (qPCR) on small5 disposable cartridges, manufactured by ST using its high-volume semiconductor manufacturing process technology. Each cartridge features 6 tiny reaction chambers (for the COVID-19 test, Alifax is using 2 chambers per sample). Each chamber supports precise heating and cooling of the reagents and samples to amplify the target genetic material, if it is present.  At the same time, exploiting the customized reagents that feature fluorescent tags developed by Alifax specifically to detect COVID-19, the Molecular Mouse determines the presence of the target genetic material in each chamber based on fluorescence intensity on multiple wavelengths.About STMicroelectronics At ST, we are 46,000 creators and makers of semiconductor technologies mastering the semiconductor supply chain with state-of-the-art manufacturing facilities. An independent device manufacturer, we work with our 100,000 customers and thousands of partners to design and build products, solutions, and ecosystems that address their challenges and opportunities, and the need to support a more sustainable world. Our technologies enable smarter mobility, more efficient power and energy management, and the wide-scale deployment of the Internet of Things and 5G technology. Further information can be found at www.st.com.About Alifax Alifax was founded in 1988 in Padova by Paolo Galiano as a result of his valuable experience in the laboratory diagnostic market with special reference to hematology, microbiology, serology and autoimmunity fields. For more information visit www.alifax.comFor Press Information Contact:Michael Markowitz Director Technical Media Relations STMicroelectronics Tel: +1 7 81 591 0354 Email: michael.markowitz@st.com Alifax S.r.l. Email: molecularmouse@alifax.com1 Ribonucleic Acid (RNA) and Deoxyribonucleic Acid (DNA) are the two main types of genetic material on which all life depends. DNA is the blueprint of life that provides the code for every cell’s activities. RNA converts that code into the instructions for making the proteins that support the structure, function, and regulation of the body’s tissues and organs. Identifying and recognizing specific RNA and DNA “codes” can detect specific pathogens. 2 Alifax had been developing 4-5 assay panels for Sepsis, and one assay to detect Zika, Dengue, Chikungunya when the COVID-19 pandemic began. Reallocating resources, they’ve rapidly developed COVID-19 assays. The Sepsis and Zika, Dengue, and Chikungunya assays will follow soon. 3 In-Vitro Diagnostic Medical Device Directive (98/79/EC) 4 Weighing just 300g (~0.66 lbs.), the Molecular Mouse has a 14cm x 7cm footprint and is 8.5cm tall. 5 The 46.9mm x 21.9mm x 8.2mm cartridge is smaller than a microscope slide. Attachments * T4295D -- Oct 29 2020 -- ST Alifax LoC coop for PCR tests_FINAL FOR PUBLICATION * T4295D -- Oct 29 2020 -- ST Alifax LoC coop for PCR tests_IMAGE

  • STMicroelectronics Establishes World’s First “Lab-in-Fab” to Advance Adoption of Piezoelectric MEMS in Singapore in Partnership with A*STAR and ULVAC
    GlobeNewswire

    STMicroelectronics Establishes World’s First “Lab-in-Fab” to Advance Adoption of Piezoelectric MEMS in Singapore in Partnership with A*STAR and ULVAC

    T4293D -- Oct 28 2020 -- Lab-in-Fab for piezo MEMS_IMAGE STMicroelectronics Establishes World’s First “Lab-in-Fab” to Advance Adoption of Piezoelectric MEMS in Singapore in Partnership with A*STAR and ULVAC * Collaboration with A*STAR’s Institute of Microelectronics (IME) and Japanese manufacturing tool vendor ULVAC, focuses on Piezo MEMS technology   * First-of-its-kind concept aims to accelerate the transition from proofs of concept to volume production, and advance the adoption of piezoelectric (Piezo) MEMS in new applications like AR/VR, medical, and 3D printing   * First wafers expected in Q2 2021, with volume production forecast at the end of 2022.Singapore, October 28, 2020 – STMicroelectronics (NYSE: STM), a global semiconductor leader serving customers across the spectrum of electronics applications and a world leader in Micro-Electromechanical Systems (MEMS) technology, announces a collaboration with A*STAR’s IME, a research institute in Singapore, and ULVAC, a leading Japanese manufacturing-tool vendor, to jointly setup and operate an 8-inch (200mm) R&D line focused on Piezo MEMS technology within ST’s existing manufacturing facility in Singapore. The first of its kind in the world, this “Lab-in-Fab” R&D line brings together three partners with leading-edge and complementary competencies in Piezo materials, Piezo MEMS technologies, and wafer-fab tools to boost innovation and accelerate development of new materials, process technologies, and ultimately, products for industry customers.The Lab-in-Fab consists of a new cleanroom area within ST’s Ang Mo Kio campus and will host tools and dedicated resources from the three parties, which include MEMS R&D and process scientists and engineers. IME’s knowledge base and industrial drive in piezo-MEMS device design, process integration, and system integration will add value to the development of the line. IME will also contribute state-of-the-art tools to help ensure a smooth product flow through to production, all within the same location. The new R&D line will also leverage existing ST resources, benefiting from the economies of scale of ST’s wafer fabs on the same campus. The “Lab-in-Fab” facility is forecast to be ready and operational with first wafers in Q2 2021 and volume production at the end of 2022.“We want to build the world’s leading R&D center for Piezo MEMS materials, technologies, and products with IME and ULVAC, with whom we have been working for a long time. This world first will be hosted in our Singapore site, a strategic location for ST,” said Benedetto Vigna, President, Analog, MEMS and Sensors Group, STMicroelectronics. “The Lab-in-Fab will offer our customers the capability to more easily go from a feasibility study to product development and high-volume manufacturing.”This collaboration enhances the existing manufacturing-process portfolio of ST Singapore and will accelerate the adoption of Piezo MEMS actuators in promising new fields of application, including MEMS Mirrors for Smart Glasses, AR Headsets and LIDAR systems, Piezoelectric Micromachined Ultrasonic Transducers (PMUT) for emerging medical applications, and Piezo Heads for Commercial and industrial 3-D Printing.“The public-private partnership between IME, ST and ULVAC has led to the creation of a unique R&D line, which will bring about novel products using piezo materials, and boost the competitiveness of our partners. These efforts will continue to anchor high-value R&D activities in Singapore and demonstrate that Singapore continues to be an attractive environment for industry leaders to innovate and grow their businesses. A*STAR is also committed to helping local SMEs tap into our technologies. We welcome companies to collaborate with IME and leverage our Lab-in-Fab facilities for proof of concept,” said Prof. Dim-Lee Kwong, Executive Director of IME.“We are proud of being a “Lab-in-Fab” partner of ST and IME in developing advanced Piezo-MEMS for numerous promising future applications. This is also a strong proof of ULVAC’s leadership in providing manufacturing technology solutions to the Piezo-MEMS industry. We are looking forward to working closely with our partners for a successful collaboration,” said Dr. Koukou SUU, Executive Officer and Senior Fellow of ULVAC. Note to editorsPiezo-based components have been widely used for decades to build actuators or sensors out of bulk piezo material. Over the past years, innovations in process technologies have allowed the MEMS industry to design and manufacture products at the wafer level using thin piezo films, opening the door for continued miniaturization, performance improvements, and cost reduction. The “Lab-in-Fab” facility comes a year after ST celebrated its 50th anniversary in Singapore in 2019, in conjunction with the opening of its brand new 8-inch (200mm) wafer fabrication facility (SG8E) in Singapore. About STMicroelectronics At ST, we are 46,000 creators and makers of semiconductor technologies mastering the semiconductor supply chain with state-of-the-art manufacturing facilities. An independent device manufacturer, we work with our 100,000 customers and thousands of partners to design and build products, solutions, and ecosystems that address their challenges and opportunities, and the need to support a more sustainable world. Our technologies enable smarter mobility, more efficient power and energy management, and the wide-scale deployment of the Internet of Things and 5G technology. Further information can be found at www.st.com.About the Institute of Microelectronics (IME) The Institute of Microelectronics (IME) is a research institute of the Agency for Science, Technology and Research (A*STAR). Positioned to bridge the R&D between academia and industry, IME's mission is to add value to Singapore's semiconductor industry by developing strategic competencies, innovative technologies and intellectual property; enabling enterprises to be technologically competitive; and cultivating a technology talent pool to inject new knowledge to the industry. Its key research areas are in Heterogeneous Integration, System-in-Package, Sensor, Actuators and Microsystems, RF & mmWave, SiC/GaN-on-SiC Power Electronics, and MedTech. For more information on IME, please visit www.ime.a-star.edu.sg. About ULVAC ULVAC, Inc., founded in 1952, contributes to the development of industry through its comprehensive vacuum technologies. We created ULVAC SOLUTIONS based on these unique technologies and long years of research, development and production innovation. We offer these solutions, for equipment, materials, vacuum components, analytic evaluation and various other services, to manufacturers of electronic components, semiconductors, solar cells, flat panel displays and other industrial equipment. For more information, please visit www.ulvac.co.jp/en/. For Press Information Contact:Mr. Dennis Tan Manager, Integrated Marketing & Communications STMicroelectronics Tel: +65 6216 5598 Email: wddennis.tan@st.comMs. Lydia Sum Assistant Head, Corporate Communications, A*STAR Tel: +65 9825 3600 Email: sumcll@hq.a-star.edu.sgULVAC, Inc. Advanced Electronics Equipment Division TEL: +81 467 89 2139 Email: elec@ml.ulvac.com   Attachments * T4293D -- Oct 28 2020 -- Lab-in-Fab for piezo MEMS_IMAGE * T4293D -- Oct 28 2020 -- Lab-in-Fab for piezo MEMS_FINAL FOR PUBLICATION_AMENDED

  • STMicroelectronics Introduces World’s First  All-in-One, Multi-Zone, Direct Time-of-Flight Module
    GlobeNewswire

    STMicroelectronics Introduces World’s First All-in-One, Multi-Zone, Direct Time-of-Flight Module

    P4281D -- Oct 27 2020 -- VL53L5 multi-zone direct ToF sensor_IMAGE STMicroelectronics Introduces World’s First All-in-One, Multi-Zone, Direct Time-of-Flight Module * Increased camera Field-of-View coverage and spatial resolution enable new features in consumer-electronics imaging systems: touch-to-focus, multiple-target identification, flash dimming, video tracking assistance * Module integrates Single Photon Avalanche Diode array, wide Field-of-View optics, and low-power on-board processing Geneva, October 27, 2020 – STMicroelectronics (NYSE: STM), a global semiconductor leader serving customers across the spectrum of electronics applications, has extended its portfolio of FlightSense™ Time-of-Flight (ToF) sensors with the world’s first 64-zone device that breaks a scene into separate areas to help an imaging system build the most detailed spatial understanding of a scene. This first-of-its-kind product comprises a 940nm Vertical Cavity Surface Emission Laser (VCSEL) light source, a System-on-Chip sensor integrating a VCSEL driver, the receiving array of Single Photon Avalanche Diodes (SPADs), and a low-power 32-bit MCU core and accelerator running sophisticated firmware. The VL53L5 retains the Class 1 certification of all ST’s FlightSense sensors and is fully eye-safe for consumer products.Housed in a miniature module, the VL53L5 ToF sensor contains optical elements in the receive aperture that creates 64 ranging zones, unlocking a host of new features and use cases.“The multi-zone VL53L5 FlightSense direct Time-of-Flight sensor uses our most advanced 40nm SPAD production process to offer outstanding 4m ranging performance and up to 64 ranging zones that help an imaging system build a detailed spatial understanding of the scene,” said Eric Aussedat, General Manager of ST’s Imaging Division. “Delivering 64x more ranging zones than previously available, the VL53L5 offers radical performance improvement in laser autofocus, touch-to-focus, presence detection, and gesture interfaces while helping developers create even more innovative imaging applications.”With a vertically integrated manufacturing model for its FlightSense sensors, ST builds its SPAD wafers on a 40nm proprietary silicon process in the Company’s state-of-the-art 12” wafer plant at Crolles, France before assembling all of the module components in ST’s back-end plants in Asia. This approach delivers exceptional quality and reliability to customers. Customer development with the VL53L5 can build on ST’s strong relationships with key smartphone and PC platform suppliers as ST has pre-integrated the sensor onto these platforms. Android and Windows device drivers are also widely available for the FlightSense products. The VL53L5 is in mass production with millions of units already shipped to leading wireless and computer manufacturers. Technical Notes to Editors: With each new generation, ST’s Time-of-Flight technology has continued to build significant high-value performance improvements across a wide range of use cases including human-presence detection to control the wakeup and hibernation of laptops or monitors and laser autofocus in hybrid focusing algorithms for smartphone cameras. The autofocus feature of ST’s FlightSense sensors is embedded in most of the highest-ranking smartphone cameras according to DXOMARK, an independent benchmark that assesses image quality.  The camera subsystem is a major factor in differentiating smartphone performance, and, within the camera, the laser autofocus assures quick, accurate focusing in low-light scenes or when capturing low-contrast targets. These scenarios present tough challenges for conventional autofocus systems but are no problem for ST’s sensors. Widely adopted by leading smartphone OEMs, laser autofocus embedding ST’s FlightSense is now shipping in more than 150 phone models. Packaged in a 6.4 x 3.0 x 1.5 mm module, the VL53L5 integrates both transmit and receive lenses into the module design and expands the Field of View (FoV) of the module to 61-degrees diagonal. This wide FoV is especially suited to detect off-center objects and ensure perfect autofocus in the corners of the image. In the ‘Laser Autofocus’ use case, the VL53L5 gathers ranging data from up-to 64 zones across the full FoV to support “Touch to Focus” and many other features. This flexibility significantly enhances smartphone/camera performance, convenience, and versatility.Further flexibility is available via the SPAD array, which can be set to favor spatial resolution, where it outputs all 64 zones at up to 15fps, or to favor maximum ranging distance, where the sensor outputs 4x4/16 zones at a frame rate of 60fps. ST’s architecture can automatically calibrate each ranging zone and direct Time-of-Flight technology allows each zone to detect multiple targets and reject reflection from the cover-glass. In addition, the FlightSense approach gathers the raw data collected by the SPAD array and performs post processing, via a proprietary, embedded MCU and accelerator before transferring the ranging data to the system host over an I2C or a SPI bus. This removes the need for a specific camera interface and powerful receiver MCU and assures high-quality, high-performance operation. For further information please go to www.st.com/vl53l5-pr.About STMicroelectronics At ST, we are 46,000 creators and makers of semiconductor technologies mastering the semiconductor supply chain with state-of-the-art manufacturing facilities. An independent device manufacturer, we work with our 100,000 customers and thousands of partners to design and build products, solutions, and ecosystems that address their challenges and opportunities, and the need to support a more sustainable world. Our technologies enable smarter mobility, more efficient power and energy management, and the wide-scale deployment of the Internet of Things and 5G technology. Further information can be found at www.st.com.For Press Information Contact: Michael Markowitz Director Technical Media Relations STMicroelectronics Tel: +1 781 591 0354 Email: michael.markowitz@st.com Attachments * P4281D -- Oct 27 2020 -- VL53L5 multi-zone direct ToF sensor_FINAL FOR PUBLICATION * P4281D -- Oct 27 2020 -- VL53L5 multi-zone direct ToF sensor_IMAGE