The Spanish had been the favourites to finish top of the group, but Luis Enrique’s players drew with Sweden and Poland in their first two outings, with a penalty miss proving costly in their second game.
FOLLOW LIVE: Build-up and team news ahead of Slovakia vs Spain
A victory is necessary if Spain are to drag themselves into the top two, while a draw could see them stay in third or even eliminated in bottom place if Poland defeat Sweden.
Slovakia started brightly with a victory over Poland but lost to Sweden last time out. They were the worse of the two sides on both occasions but have managed to record three points so far. Another win, or a draw coupled with Sweden avoiding defeat, would see them advance to the last 16.
Here’s everything you need to know about the Euro 2020 match.
When is it?
The match will kick off at 5pm BST in Sevilla.
How can I watch it?
ITV will air the game in the UK, with the ITV Hub platform streaming the match.
Slovakia: Dúbravka, Pekarík, Šatka, Duda, Škriniar, HuboÄan, Hamšík, Haraslín, Kucka, Mak, Hromada
Spain: Simon, Azpilicueta, García, Laporte, Alba, Koke, Busquets, Pedri, Sarabia, Moreno, Morata
Spain have struggled to create clear-cut chances and to score, but they are still the overwhelming favourites for good reason. Slovakia have not performed well so far and now go up against the most difficult test of the group stage. Unless Spain are yet again their own worst enemy, expect a comfortable victory for the hosts here. Slovakia 0-2 Spain.