Frank Lampard's side are in fine form and head into this Group E clash off the back of a fifth win in a row, a victory at Newcastle United on Saturday with Tammy Abraham on the scoresheet at St James Park.
That win took the Blues top of the Premier League, albeit temporarily, with the visitors on Tuesday also in good shape in European competition as well as back home. They travel to France top of their group after two wins from their three matches so far, with another three points likely to be good enough to secure passage to the knockout stages of the tournament with two games remaining.
Chelsea won the corresponding fixture at Stamford Bridge with two Timo Werner penalties and an Abraham goal more than enough after Dalbert was controversially dismissed early on.
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Here's everything you need to know:
When is the match?
The game kicks off on Tuesday 24 November.
What time is it?
Kick-off is 5.55pm GMT.
How can I watch it?
The match is being broadcast on BT Sport 3.
Subscribers can also stream the game live via the BT Sport website.
Rennes: Gomis, Traore, Nyamsi, Da Silva, Truffert, Nzonzi, Camavinga, Bourigeaud, Doku, Guirassy, Lea Siliki
Chelsea: Mendy; Azpilicueta, Thiago Silva, Zouma, Chilwell; Kovacic, Jorginho, Mount; Werner, Abraham, Hudson-Odoi
What are the odds?
The Blues have been very impressive of late and should have too much for their French hosts. Rennes 0-2 Chelsea