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Pregistry Study Shows an Increase in Stress Related to the COVID-19 Pandemic Among Pregnant Women

·4-min read

Race and Ethnicity, Country of Residence, and Levels of Family and Community Support Indicators of Differing Stress Levels Worldwide Caused by COVID-19

LOS ANGELES, October 14, 2021--(BUSINESS WIRE)--New data released today from Pregistry, a global leader in the development and execution of studies to assess the safety of medications and vaccines when used during pregnancy, show an increase in stress levels among pregnant and postpartum women during the COVID-19 pandemic. The study was conducted by Pregistry's CEO, Dr. Diego Wyszynski and a team of collaborators around the world. It is one of the first research projects to explore stress levels among pregnant and postpartum women during the COVID-19 pandemic.

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Pregistry study shows an increase in stress levels among pregnant and postpartum women during the COVID-19 pandemic (Photo: Business Wire)

Published in The Journal of Maternal-Fetal & Neonatal Medicine, "Stress levels among an international sample of pregnant and postpartum women during the COVID-19 pandemic" was an anonymous, online, cross-sectional survey of 7,185 women in 64 countries between May and June 2020. The survey was hosted on the Pregistry platform and made available in 12 languages, with respondents sought through a variety of social media platforms and parenting forums. Results showed significant stress scores among women 35 years of age and older. As the COVID-19 pandemic continues, there is a growing, yet limited, body of evidence demonstrating its impact on maternal health.

"The medical community has thoroughly documented the profound impact of stress on the health of pregnant women and their children," said Pregistry's Founder and CEO, Dr. Diego Wyszynski. "Understanding the breadth and depth of COVID-19 related stress during pregnancy is vital in knowing the repercussions that coronavirus will have on our next generation."

Higher stress scores were found among women in Africa, Asia and the Pacific, the Middle East, and North America compared with those in Europe. When race and ethnicity were included in the model, black women were found to have higher stress compared to white women. In addition, the level of family and community support was inversely associated with level of stress. Being younger than 35 years of age, living with a partner or spouse, having a college degree, being an essential worker, having medical coverage, and the presence of social support were all associated with a decrease in stress level.

"The information we've gathered in this study can be used to create data-driven policies and programs that will work to alleviate stress and mitigate its effect on pregnant individuals. Understanding the stress experienced by pregnant and postpartum women at this time should be considered a public health priority," said Dr. Wyszynski.

Given the profound effect that stress can have on the mental wellbeing and health of pregnant and postpartum women and their children, interventions designed to improve the mental health of this population during the pandemic would have a wide-reaching impact. Studies like these seek to help improve the policies and interventions that can mitigate the impact of stress, not only for this group of women, but for the wider public.

The full version of this study is available in The Journal of Maternal-Fetal and Neonatal Medicine. The study was sponsored by Pregistry, an independent research institution, as part of its mission-centric work in helping to create a world where all pregnant people and their healthcare providers have access to high-quality data about the reproductive risks of medicines and vaccines.

About Pregistry

Pregistry is a global leader in the development and execution of observational studies to assess the safety of medications and vaccines when used during pregnancy. With over 70 pregnancy specialists, covering a range of clinical, preclinical, safety, regulatory, marketing, and IT needs, the focus is on making sure that both mother and baby are healthy and safe and that prescribers have the information needed to be able to explain the potential benefits and risks of medications during pregnancy. Pregistry also offers pregnant women a safe space to connect with a global community of experts and peers at no cost. To learn more, please visit:

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Diego Wyszynski, MD, MHS, PhD
Chief Executive Officer

Abigail Baker, MA
Director of Communications

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