City were 3-0 victors against the Greek outfit in the reverse fixture earlier in November, with Gabriel Jesus, Ferran Torres and Joao Cancelo netting at the Etihad Stadium.
With the Premier League team perfect in the competition so far this term, they will be fairly confident of replicating their last result against Pedro Martins’ side and moving to 12 points from 12 in Group C – effectively confirming their spot in the last 16.
Here’s everything you need to know about the Champions League meeting in Greece.
When is it?
The match kicks off at 17:55 BST on Wednesday 25 November.
How can I watch it?
The game will air live on BT Sport. Subscribers can also stream it on the BT Sport website and app.
Olympiacos: Jose Sa; Drager, Semedo, Cisse, Rafinha; M'Vila, Ba, Camara; Pepe, Fortounis, Masouras
Man City: Ederson; Cancelo, Dias, Stones, Mendy; Foden, Rodri, GündoÄan; Sterling, Agüero, Silva
Man City: 2/7
Since City played Olympiacos at the start of the month, Guardiola’s side have drawn one – versus Liverpool – and lost one – against Tottenham. A brief break from the Premier League, against opposition that didn’t cause much trouble last time out, might just be exactly what City need. Expect them to respond positively here. Olympiacos 0-2 Man City.