Ms Banes, best known for starring in David Fincher’s Gone Girl, was crossing the street when she was struck by a motorised scooter while on the way to meet her wife, Kathryn Kranhol.
The driver of the scooter left the scene and is currently being sought by police.
Ms Banes was taken to Mount Sinai Morningside hospital with a traumatic brain injury and died on Monday, June 14.
A representative told Entertainment Tonight: “We are heartsick over Lisa’s tragic and senseless passing.
“She was a woman of great spirit, kindness and generosity and dedicated to her work, whether on stage or in front of a camera and even more so to her wife, family and friends.
“We were blessed to have had her in our lives.”
A New York Police Department spokesperson said no arrests have been made.
She also appeared opposite Tom Cruise in the 1988 film, Cocktail, and in TV series including Nashville and Masters of Sex.
Actor Seth MacFarlane said: “I am deeply saddened at the news of Lisa Banes’ passing.
“We had the good fortune to work with her on The Orville this past year. Her stage presence, magnetism, skill and talent were matched only by her unwavering kindness and graciousness toward all of us. A tremendous loss…”
Ms Banes’s friend, singer Jill Sobule, wrote: Just busted. Lisa Banes was magnificent, hilarious, and big-hearted – always helped me through the hard times. She was so beloved by so many.”