Global Clinical Genomics Markets Report 2021: Mergers, Acquisitions, and Partnerships Accelerate Adoption of Clinical Genomics
Dublin, April 14, 2021 (GLOBE NEWSWIRE) -- The "Clinical Genomics Report: The Interplay Between Clinical Research & Clinical Diagnostics" report has been added to ResearchAndMarkets.com's offering.
This "Clinical Genomics Report: The Interplay Between Clinical Research and Clinic Diagnostics" provides an in-depth analysis of differences in product characteristics related to data processing, analysis, knowledge extraction and reporting of findings (including the type of content integrated for meaningful extraction), and compliance and security mechanisms. Both clinical end-users and commercial companies who require insight into this expanding industry and its providers and products will benefit from the critical, investigative, and qualitative report.
This new, qualitative report provides an in-depth analysis across the complex, multi-step clinical genomics data process (which includes genomic data generation, data flow, and data warehousing), clinical genomics data solution providers, market trends, technologies impacting clinical genomics applications development, clinical genomics adoption challenges, and detailed challenges & needs analysis as identified in discussions with clinical end-users.
The report is unique, in that it is not a predictive market research report, but rather builds on data gathered from many end-user interviews combined with an extensive analysis of the clinical genomics sector.
Report Contents:
Leading medical organizations have established precision medicine programs that support personalized patient treatment. Implementation of clinical genomics applications and enterprise-wide clinical data warehouses are considered the foundation for successful genomic medicine programs. Innovative technological advancements have allowed us to sequence and uncover mutational events at an unprecedented scale while facilitating linking genomic data to high-quality clinical data and diagnosis.
Medical organizations understand the benefit of being empowered by data-driven approaches to reduce operational costs and time and to provide researchers and clinicians what is necessary to decipher critical research data and data for clinical decision making. However, technical and scientific limitations still need to be addressed for optimized and universal use of various data sources for both clinical and research purposes.
While data production is no longer a challenge, and targeted panels - and to some extent, whole-exome sequencing - are well adopted, the expected dramatic rise in whole-genome sequencing will result in unforeseeable quantities of data at the clinical level that needs to be managed, understood, and communicated. Low-cost sequencing of whole genomes at population scale is already in existence, but not yet widespread in the clinic, as many observed changes at the genome level cannot yet be fully interpreted or explain an existing phenotype.
Scalable, fully automated analysis and knowledge extraction solutions incorporating rich annotation information are necessary to overcome these challenges. With massive quantities of NGS data (linked to different clinical and other types of data), artificial intelligence and machine learning are hailed as pivotal solutions to address the data interpretation and knowledge extraction challenges and to advance the clinical application of genomics.
Despite increasing efforts and investments in implementing clinical applications and building data solutions, many organizations are still challenged with the multi-faceted complexities in transforming to become data-driven. Implementations are challenged by ineffective data sharing, scalability and automation issues, non-optimized data generation and data flow approaches and non-standardized data from numerous sources.
Implementing a complex clinical data warehouse presents many challenges starting with the various data sources it needs to support and the tools required to view the clinical information. Ingestion of data of different types and origins with relevant metadata; data transformation, standardization, and cleansing to support the needs of a diverse set of end-users in both the clinical and research settings; and varied end-users with individual needs and computation capabilities are all important considerations.
Clinical interviews detailed challenges associated with creating a workflow that incorporates a clinical data warehouse connecting clinical research with clinical diagnostics and vice versa. This important workflow leads to efficient clinical decision-making and reporting findings between clinical research and the clinic, which can optimize clinical outcomes and patient treatment.
Key Topics Covered:
1. THE CLINICAL DIAGNOSTICS & MOLECULAR PROFILING WORKFLOW
Clinical Genomics Workflow End Users/Personas
Mapping End Users to the Clinical Genomics Workflow
Clinical Information Delivery
2. THE PRECISION MEDICINE VALUE CHAIN
3. LEADING MEDICAL ORGANIZATIONS PLATFORM AND INFRASTRUCTURE PREFERENCES IN SUPPORT OF THEIR CLINICAL GENOMICS WORKFLOWS
Implementations and Choices of Molecular Profiling and Genetic Testing Processes
Medical Organizations' Clinical Genetic Testing Labs
Testing Lab Selection Criteria
Platforms and Infrastructures Currently Implemented at Leading Medical Organizations
Adoption of Commercial and Internally Developed Platforms, Tools, and Services
Medical Organizations Platform and Infrastructure Preferences
Profiles of Leading Medical Organizations
Cedars-Sinai
Emory Healthcare
Geisinger Health Systems
Intermountain Healthcare
Kaiser Permanente
Mayo Clinic
MD Anderson Cancer Center
Moffitt Cancer Center
Mount Sinai Health System
Nationwide Children's Hospital
Partners HealthCare
Sanford Health
St. Jude Children's Hospital
Vanderbilt University Medical Center
4. MEDICAL INDUSTRY CHALLENGES
Clinical Genomics - Unmet Needs and Challenges
Technical Challenges Associated with Scaling Clinical Genomics Applications
Scientific Challenges Associated with the Implementation of Clinical Genomics
Non-Technical / Scientific Challenges Associated with the Implementation of Clinical Genomics Applications
5. GENOMIC DATA GENERATION, DATA FLOW, AND DATA WAREHOUSING
Rethinking Optimized Genomic Data Generation and Data Flow
Structures of Successful Big Data Platforms
Scalable Data Generation and Data Flow Lacking Data Standards
Slow Integration of Clinical Genomics Data with Other Clinical/Patient Data
Current EMR/EHR Systems Do Not Support Genomics Data
Variant Data Warehousing for Data Analysis, Mining, and Querying
Enterprise Data Platform Architecture
Integration of Various Types of Data
A Data Warehouse That Supports Clinical Research
Data Warehousing and Fast Data Processing Requires a Scalable Infrastructure
The Ideal Variant Data Analysis and Query Platform
Data Warehouse versus a Data Lake
Cloud Is the Preferred Infrastructure
6. CLINICAL GENOMICS DATA SOLUTIONS
Genomic Data Infrastructures/Platforms for Data Storage, Processing, and Analysis
Scaled Data Storage and Computing Solutions
Clinical Genomics Data Platforms
Integrated Genomic Workflow
Data Processing Speed, Scalability, and Flexibility
Clinical Data Management & Knowledge Extraction
Clinico-Genomic Data Management and Integration
Genomic/Variant Data Querying and Analysis
Variant Data Interpretation/Decision Making/Reporting
Tertiary Analysis - Sequence Data Interpretation and Insight Generation
Tertiary Analysis - Embedded Interpretation Content for Insight Generation
Data Processing, Knowledge Extraction, and Reporting Companies Side-by-Side
7. CLINICAL GENOMICS MARKET TRENDS
Factors Impacting Clinical Sequencing Adoption
Genetic Testing and Molecular Profiling Trends
The Increasing Trend of Clinical Genetic Testing
Clinical Genomics Applications to Be Established in the Clinic as a Routine
Routine Genomic Applications Established over the Next Three to Five Years
Requirements to Establish Genomic Applications as a Routine
Mergers, Acquisitions, and Partnerships Accelerate Adoption of Clinical Genomics
Agilent Is Building Integrated, Complete Clinical Workflow Solutions
Illumina's M&As Suggest the Goal of a Fully Integrated Sequencing Solution
Roche Is Expanding its Diagnostics Business
Thermo Fisher Scientific Is Strengthening Its Presence in the Clinical Sector
QIAGEN Is Pushing the Molecular Diagnostics and Clinical Research Markets
Other Acquisitions and Partnerships
8. TECHNOLOGIES IMPACTING THE IMPLEMENTATION OF CLINICAL GENOMICS & MOLECULAR PROFILING APPLICATIONS
3rd and 4th Generation Sequencing Technology
Artificial Intelligence/Machine Learning Applications
AI in Healthcare Adoption Drivers
Liquid Biopsy in Clinical Diagnostics
Liquid Biopsy Clinical Applications
Long-Read Sequencing Technology
Real-World Data / Real-World Evidence
The FDA Is Attempting to Define RWD and RWE
An Uptick of RWD and RWE Publications
The Benefits of Real-World Evidence
The Challenges of Using RWD and RWE
An Active Playing Field of Commercial RWD Players
Clinical Genomics Adoption Challenges
9. COVID-19, THE HEALTHCARE DISRUPTER
Diagnostics - Commercial Companies Revamping
Diagnostics Companies Quickly Pivoted
COVID-19, a Disrupter, but also an Opportunity
Viral Sequencing Reveals How SARSCo-V-2 Evolves and Spreads
COVID-19 Resulted in Unprecedented Data Sharing
COVID-19 and the Massive Disruptions to Clinical Trials Processes
10. COMMERCIAL CLINICAL SOLUTIONS / PRODUCT PROVIDERS
Company Profiles
BC Platforms
Bluebee (an Illumina company)
Color
Congenica
DNAnexus
Fabric Genomics
Foundation Medicine
Freenome
Genoox
Genuity Science
Google Life Sciences
GRAIL
Helix
Illumina
Invitae
PierianDx
QIAGEN
Seven Bridges
SOPHiA Genetics
Tempus
11. THE FUNDING SITUATION
12. APPENDIX
Clinical Genomics End User Types
The Computational Scientist/Bioinformatician
The Data Scientist
The Non-Computational Collaborator
The Genetic Counselor
The Clinical Geneticist
The Physician
The Patient
13. ABBREVIATIONS
For more information about this report visit https://www.researchandmarkets.com/r/hfqr98
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