Presentation Highlights Recent Platform Development Providing the Potential to Readily Exchange T cell Epitopes to Target Diverse T cell Populations
CAMBRIDGE, Mass., Dec. 02, 2019 (GLOBE NEWSWIRE) -- Cue Biopharma, Inc. (CUE), a clinical-stage biopharmaceutical company engineering a novel class of injectable biologics to selectively engage and modulate targeted T cells within the body, announced today Dr. John Ross, Ph.D., vice president of protein therapeutics, will give a presentation highlighting the potential of the company’s proprietary therapeutic platform Immuno-STAT™ (Selective Targeting and Alteration of T cells) and associated Cue Biopharma Neo-STAT™ platform development at the World Vaccine & Immunotherapy Congress taking place on Dec. 2-5, 2019 at the San Francisco Airport Marriott Waterfront.
Title: Immuno-STAT™ and Neo-STAT™ – Therapeutic platforms for the selective modulation of antigen-specific T cells
Presenter: John Ross, Ph.D., vice president, protein therapeutics
Date & Time: Dec. 5 at 12:10 p.m. PT
“This presentation highlights the core strength and therapeutic potential of our Immuno-STAT platform to selectively target and drug antigen-specific T cells directly in the patient,” said Dr. Anish Suri, Ph.D. president and chief scientific officer of Cue Biopharma. “Furthermore, the evolution of the Neo-STAT platform may allow for the generation of therapeutic molecules that can incorporate diverse T cell epitopes, including peptides bearing post-translational modifications and those derived from tumor neo-antigens, thereby broadening our reach to novel opportunities in personalized immunotherapy. The Neo-STAT platform exploits chemical attachment of T cell epitopes to stabilized HLA molecules, along with desired co-stimulatory signals, to generate polyspecific therapeutic molecules for activating tumor-specific T cells directly in the patient.”
“CUE-101, our lead clinical candidate, is exemplary of the Immuno-STAT platform and is currently being dosed in patients suffering from recurrent and metastatic head and neck cancer,” said Daniel Passeri, chief executive officer of Cue Biopharma. “Through the deployment of the Cue Biopharma Neo-STAT platform, we can potentially expand patient reach and exploit significant time and cost-related efficiencies.”
About Cue Biopharma
Cue Biopharma, a clinical-stage biopharmaceutical company, is engineering a novel class of injectable biologics to selectively engage and modulate targeted T cells within the body to transform the treatment of cancer and autoimmune diseases. The company’s proprietary Immuno-STAT™ (Selective Targeting and Alteration of T cells) platform is designed to harness the body’s intrinsic immune system without the need for ex vivo manipulation.
Headquartered in Cambridge, Massachusetts, we are led by an experienced management team and independent Board of Directors with deep expertise in the design and clinical development of protein biologics, immunology and immuno-oncology treatments.
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